Mehapt Bali, Ph.D.  (2006)
Currently: Adjunct Professor, Koc Universitesi Lojmanlari, Turkey
Mentor at CUNY: Dr. Corinne Michels, Queens College

Publications at CUNY

Bali, M., B. Zhang, K.A. Morano, and C.A. Michels, 2003. The Hsp90 molecular chaperone complex regulates maltose induction and stability of the Saccharomyces MAL gene transcription activator Mal63p. J. Biol. Chem. 278: 47441-47448.

Wang, X., M. Bali, I. Medintz, and C.A. Michels, 2002. Intracellular maltose is sufficient to induce MAL gene expression in Saccharomyces cerevisiae. Eukaryot. Cell 1: 696-703.

Danzi, S.E., M. Bali, and C.A. Michels, 2003. Clustered-charge to alanine-scanning mutagenesis of the Mal63 MAL-activator C-terminal regulatory domain. Curr. Genet. 44: 173-183.

Li Hui, Ph.D.  (2006)
Currently: Postdoctoral Fellow, Novartis Research Institute, Cambridge, MA
Mentor at CUNY: Dr. David Foster, Hunter College

Publications at CUNY
Hui L, Zheng Y, Yan Y, Bargonetti J, Foster DA.  Mutant p53 in MDA-MB-231 breast cancer cells is stabilized by elevated phospholipase D activity and contributes to survival signals generated by phospholipase D.  Oncogene. 2006 Nov 23;25(55):7305-10.

Rodrik V, Gomes E, Hui L, Rockwell P, Foster DA.  Myc stabilization in response to estrogen and phospholipase D in MCF-7 breast cancer cells.  FEBS Lett. 2006 Oct 16;580(24):5647-52.

Zheng Y, Rodrik V, Toschi A, Shi M, Hui L, Shen Y, Foster DA.  Phospholipase D couples survival and migration signals in stress response of human cancer cells.  J Biol Chem. 2006 Jun 9;281(23):15862-8.

Hui L, Rodrik V, Pielak RM, Knirr S, Zheng Y, Foster DA.  mTOR-dependent suppression of protein phosphatase 2A is critical for phospholipase D survival signals in human breast cancer cells.  J Biol Chem. 2005 Oct 28;280(43):35829-35.
 
Chen X, Hui L, Foster DA, Drain CM.  Efficient synthesis and photodynamic activity of porphyrin-saccharide conjugates: targeting and incapacitating cancer cells.  Biochemistry. 2004 Aug 31;43(34):10918-29.

Hui L, Abbas T, Pielak RM, Joseph T, Bargonetti J, Foster DA.
Phospholipase D elevates the level of MDM2 and suppresses DNA damage-induced increases in p53.  
Mol Cell Biol. 2004 Jul;24(13):5677-86.

Abbas T, White D, Hui L, Yoshida K, Foster DA, Bargonetti J.  Inhibition of human p53 basal transcription by down-regulation of protein kinase Cdelta.  J Biol Chem. 2004 Mar 12;279(11):9970-7.

Marie McGovern, Ph.D.  (2006)
Currently: Postdoctoral Research Fellow, NYU School of Medicine, New York, NY
Mentor at CUNY: Dr. Cathy Savage-Dunn, Queens College

Publications at CUNY
McGovern, M., L. Yu, M. Kosinski, D. Greenstein and C. Savage-Dunn. 2007. A Role for Sperm in Regulation of Egg-Laying in the Nematode C. elegans. BMC Dev. Biol., 7:41.

Kenyon Ogburn, Ph.D.  (2006)
Currently:  Postdoctoral Fellow, Weill Medical College of Cornell University, New York, NY
Mentor at CUNY: Dr. Maria Figueiredo-Pereira, Hunter College

Publications at CUNY
Ogburn KD, Figueiredo-Pereira ME.  Cytoskeleton/endoplasmic reticulum collapse induced by prostaglandin J2 parallels centrosomal deposition of ubiquitinated protein aggregates.  J Biol Chem. 2006 Aug 11;281(32):23274-84.

Wang Z, Aris VM, Ogburn KD, Soteropoulos P, Figueiredo-Pereira ME.  Prostaglandin J2 alters pro-survival and pro-death gene expression patterns and 26 S proteasome assembly in human neuroblastoma cells.  J Biol Chem. 2006 Jul 28;281(30):21377-86.

Ogburn KD, Bottiglieri T, Wang Z, Figueiredo-Pereira ME. Prostaglandin J2 reduces catechol-O-methyltransferase activity and enhances dopamine toxicity in neuronal cells.  Neurobiol Dis. 2006 May;22(2):294-301.

Li Z, Jansen M, Ogburn K, Salvatierra L, Hunter L, Mathew S, Figueiredo-Pereira ME.
Neurotoxic prostaglandin J2 enhances cyclooxygenase-2 expression in neuronal cells through the p38MAPK pathway: a death wish?  J Neurosci Res. 2004 Dec 15;78(6):824-36.

Jason Rauceo, Ph.D.  (2006)
Currently: Postdoctoral Fellow, Columbia University, New York, NY
Mentor at CUNY: Dr. Peter Lipke, Brooklyn College

Publications at CUNY
Dranginis AM, Rauceo JM, Coronado JE, Lipke PN.  A biochemical guide to yeast adhesins: glycoproteins for social and antisocial occasions.  Microbiol Mol Biol Rev. 2007 Jun;71(2):282-94.

Rauceo JM, De Armond R, Otoo H, Kahn PC, Klotz SA, Gaur NK, Lipke PN.  Threonine-rich repeats increase fibronectin binding in the Candida albicans adhesin Als5p.  Eukaryot Cell. 2006 Oct;5(10):1664-73.
 
Klotz SA, Gaur NK, Rauceo J, Lake DF, Park Y, Hahm KS, Lipke PN.  Inhibition of adherence and killing of Candida albicans with a 23-Mer peptide (Fn/23) with dual antifungal properties.  Antimicrob Agents Chemother. 2004 Nov;48(11):4337-41.
 
Rauceo JM, Gaur NK, Lee KG, Edwards JE, Klotz SA, Lipke PN.  Global cell surface conformational shift mediated by a Candida albicans adhesin.  Infect Immun. 2004 Sep;72(9):4948-55.

Klotz SA, Gaur NK, Lake DF, Chan V, Rauceo J, Lipke PN.  Degenerate peptide recognition by Candida albicans adhesins Als5p and Als1p.  Infect Immun. 2004 Apr;72(4):2029-34.

Vanessa Rodrik, Ph.D.  (2006)
Currently: Postdoctoral Fellow, Memorial Sloan Kettering Cancer Center, New York, NY
Mentor at CUNY: Dr. David Foster, Hunter College

Publications at CUNY
Rodrik V, Gomes E, Hui L, Rockwell P, Foster DA.  Myc stabilization in response to estrogen and phospholipase D in MCF-7 breast cancer cells.  FEBS Lett. 2006 Oct 16;580(24):5647-52.

Zheng Y, Rodrik V, Toschi A, Shi M, Hui L, Shen Y, Foster DA.  Phospholipase D couples survival and migration signals in stress response of human cancer cells.  J Biol Chem. 2006 Jun 9;281(23):15862-8.
 
Hui L, Rodrik V, Pielak RM, Knirr S, Zheng Y, Foster DA.  mTOR-dependent suppression of protein phosphatase 2A is critical for phospholipase D survival signals in human breast cancer cells.  J Biol Chem. 2005 Oct 28;280(43):35829-35.

Rodrik V, Zheng Y, Harrow F, Chen Y, Foster DA.  Survival signals generated by estrogen and phospholipase D in MCF-7 breast cancer cells are dependent on Myc.  Mol Cell Biol. 2005 Sep;25(17):7917-25.

Chen Y, Rodrik V, Foster DA.  Alternative phospholipase D/mTOR survival signal in human breast cancer cells.  Oncogene. 2005 Jan 20;24(4):672-9.

Judy Zhu, Ph.D.  (2006)
Currently: Postdoctoral Fellow, Columbia University, New York, NY
Mentor at CUNY: Dr. Jesus Angulo, Hunter College

Publications at CUNY
Zhu JP, Xu W, Angulo JA.  Distinct mechanisms mediating methamphetamine-induced neuronal apoptosis and dopamine terminal damage share the neuropeptide substance p in the striatum of mice.  Ann N Y Acad Sci. 2006 Aug;1074:135-48.

Zhu JP, Xu W, Angulo JA.  Methamphetamine-induced cell death: selective vulnerability in neuronal subpopulations of the striatum in mice.  Neuroscience. 2006 Jun 30;140(2):607-22.

Zhu JP, Xu W, Angulo N, Angulo JA.  Methamphetamine-induced striatal apoptosis in the mouse brain: comparison of a binge to an acute bolus drug administration.  Neurotoxicology. 2006 Jan;27(1):131-6.
 
Xu W, Zhu JP, Angulo JA.  Induction of striatal pre- and postsynaptic damage by methamphetamine requires the dopamine receptors.  Synapse. 2005 Nov;58(2):110-21.

Zhu JP, Xu W, Angulo JA.  Disparity in the temporal appearance of methamphetamine-induced apoptosis and depletion of dopamine terminal markers in the striatum of mice.  Brain Res. 2005 Jul 12;1049(2):171-81.

Loonam TM, Noailles PA, Yu J, Zhu JP, Angulo JA.  Substance P and cholecystokinin regulate neurochemical responses to cocaine and methamphetamine in the striatum.  Life Sci. 2003 Jun 27;73(6):727-39.

Faith Harrow, Ph.D.  (2005)
Currently: Postdoctoral Fellow, National Institutes of Health, Bethesda, MD
Mentor at CUNY:  Dr. Ben Ortiz, Hunter College

Publications at CUNY
Gomos-Klein J, Harrow F, Alarcon J, Ortiz BD.  CTCF-Independent, but Not CTCF-Dependent, Elements Significantly Contribute to TCR-alpha Locus Control Region Activity.  J Immunol. 2007 Jul 15;179(2):1088-95.

Harrow F, Ortiz BD.  The TCR-alpha locus control region specifies thymic, but not peripheral, patterns of TCR-alpha gene expression.  J Immunol. 2005 Nov 15;175(10):6659-67.

Rodrik V, Zheng Y, Harrow F, Chen Y, Foster DA.  Survival signals generated by estrogen and phospholipase D in MCF-7 breast cancer cells are dependent on Myc.  Mol Cell Biol. 2005 Sep;25(17):7917-25.
 
Harrow F, Amuta JU, Hutchinson SR, Akwaa F, Ortiz BD.  Factors binding a non-classical Cis-element prevent heterochromatin effects on locus control region activity.  J Biol Chem. 2004 Apr 23;279(17):17842-9.

Bishop JD, Moon BC, Harrow F, Ratner D, Gomer RH, Dottin RP, Brazill DT.  A second UDP-glucose pyrophosphorylase is required for differentiation and development in Dictyostelium discoideum.  J Biol Chem. 2002 Sep 6;277(36):32430-7.

Ortiz BD, Harrow F, Cado D, Santoso B, Winoto A.  Function and factor interactions of a locus control region element in the mouse T cell receptor-alpha/Dad1 gene locus.  J Immunol. 2001 Oct 1;167(7):3836-45.

Desmond Jackson, Ph.D.  (2005)
Currently: Postdoctoral Fellow, City of Hope Cancer Center, Duarte, CA
Mentor at CUNY: Dr. David Foster, Hunter College

Publications at CUNY
Jackson D, Zheng Y, Lyo D, Shen Y, Nakayama K, Nakayama KI, Humphries MJ, Reyland ME, Foster DA.  Suppression of cell migration by protein kinase Cdelta.  Oncogene. 2005 Apr 21;24(18):3067-72.

Jackson DN, Foster DA.
The enigmatic protein kinase Cdelta: complex roles in cell proliferation and survival.  FASEB J. 2004 Apr;18(6):627-36.  

Zhong M, Shen Y, Zheng Y, Joseph T, Jackson D, Foster DA.   Phospholipase D prevents apoptosis in v-Src-transformed rat fibroblasts and MDA-MB-231 breast cancer cells.  Biochem Biophys Res Commun. 2003 Mar 14;302(3):615-9.

Xu L, Frankel P, Jackson D, Rotunda T, Boshans RL, D'Souza-Schorey C, Foster DA.  Elevated phospholipase D activity in H-Ras- but not K-Ras-transformed cells by the synergistic action of RalA and ARF6.
Mol Cell Biol. 2003 Jan;23(2):645-54.

Zhong M, Joseph T, Jackson D, Beychenok S, Foster DA.  Elevated phospholipase D activity induces apoptosis in normal rat fibroblasts.  Biochem Biophys Res Commun. 2002 Nov 8;298(4):474-7.

Jun Liang, Ph.D.  (2005)
Currently: Postdoctoral Research Associate, Memorial Sloan-Kettering Cancer Center, NY
Mentor at CUNY: Dr. Cathy Savage-Dunn, Queens College

Publications at CUNY
Liang, J., L. Yu, J. Yin, and C. Savage-Dunn. 2007. Transcriptional Repressor and Activator Activities of SMA-9 Contribute Differentially to BMP-Related Signaling Outputs. Dev. Biol.,305:714-725

Liang, J., R. Lints, M.L. Foehr, R. Tokarz, L. Yu, S.W. Emmons, J. Liu, and C. Savage-Dunn. 2003. The Caenorhabditis elegans schnurri homolog, sma-9, mediates stage- and cell type-specific responses to dbl-1 BMP-related Signaling. Development, 130:6453-6464.

Timothy Spencer, Ph.D.  (2005)
Currently:  Postdoctoral Fellow, Columbia University, New York, NY
Mentor at CUNY: Dr. Marie Filbin, Hunter College

Publications at CUNY
Cao Z, Gao Y, Bryson JB, Hou J, Chaudhry N, Siddiq M, Martinez J, Spencer T, Carmel J, Hart RB, Filbin MT. The cytokine interleukin-6 is sufficient but not necessary to mimic the peripheral conditioning lesion effect on axonal growth.  J Neurosci. 2006 May 17;26(20):5565-73.

Domeniconi M, Zampieri N, Spencer T, Hilaire M, Mellado W, Chao MV, Filbin MT. MAG induces regulated intramembrane proteolysis of the p75 neurotrophin receptor to inhibit neurite outgrowth.   Neuron. 2005 Jun 16;46(6):849-55.
 
Spencer T, Filbin MT.  A role for cAMP in regeneration of the adult mammalian CNS.
J Anat. 2004 Jan;204(1):49-55.

Gao Y, Deng K, Hou J, Bryson JB, Barco A, Nikulina E, Spencer T, Mellado W, Kandel ER, Filbin MT.  Activated CREB is sufficient to overcome inhibitors in myelin and promote spinal axon regeneration in vivo.  Neuron. 2004 Nov 18;44(4):609-21.

Spencer T, Domeniconi M, Cao Z, Filbin MT.  New roles for old proteins in adult CNS axonal regeneration.  Curr Opin Neurobiol. 2003 Feb;13(1):133-9.
 
Domeniconi M, Cao Z, Spencer T, Sivasankaran R, Wang K, Nikulina E, Kimura N, Cai H, Deng K, Gao Y, He Z, Filbin M.  Myelin-associated glycoprotein interacts with the Nogo66 receptor to inhibit neurite outgrowth.  Neuron. 2002 Jul 18;35(2):283-90.

David E. White, Ph.D.  (2005)
Currently: Postdoctoral Fellow, University of Pennsylvania, Philadelphia, PA
Mentor at CUNY:  Dr. Jill Bargonetti, Hunter College

Publications at CUNY
Boamah EK, White DE, Talbott KE, Arva NC, Berman D, Tomasz M, Bargonetti J. Mitomycin-DNA adducts induce p53-dependent and p53 independent cell death pathways.  ACS Chem Biol. 2007 Jun 15;2(6):399-407.

White DE, Talbott KE, Arva NC, Bargonetti J.  Mouse double minute 2 associates with chromatin in the presence of p53 and is released to facilitate activation of transcription.  Cancer Res. 2006 Apr 1;66(7):3463-70.

Arva NC, Gopen TR, Talbott KE, Campbell LE, Chicas A, White DE, Bond GL, Levine AJ, Bargonetti J.  A chromatin-associated and transcriptionally inactive p53-Mdm2 complex occurs in mdm2 SNP309 homozygous cells.  J Biol Chem. 2005 Jul 22;280(29):26776-87.

Abbas T, White D, Hui L, Yoshida K, Foster DA, Bargonetti J. Inhibition of human p53 basal transcription by down-regulation of protein kinase Cdelta.  J Biol Chem. 2004 Mar 12;279(11):9970-7.

Xiao G, White D, Bargonetti J.  p53 binds to a constitutively nucleosome free region of the mdm2 gene.  Oncogene. 1998 Mar 5;16(9):1171-81.

Bargonetti J, Chicas A, White D, Prives C.  p53 represses Sp1 DNA binding and HIV-LTR directed transcription.  Cell Mol Biol.  1997 Nov;43(7):935-49.

Tarek Abbas, Ph.D.  (2004)
Currently: Postdoctoral Fellow, University of Virginia, Charlottesville, VA
Mentor at CUNY: Dr. Jill Bargonetti

Publications at CUNY
Hui L, Abbas T, Pielak RM, Joseph T, Bargonetti J, Foster DA.  Phospholipase D elevates the level of MDM2 and suppresses DNA damage-induced increases in p53.  Mol Cell Biol. 2004 Jul;24(13):5677-86.

Abbas T, White D, Hui L, Yoshida K, Foster DA, Bargonetti J.  Inhibition of human p53 basal transcription by down-regulation of protein kinase Cdelta.  J Biol Chem. 2004 Mar 12;279(11):9970-7.

Abbas T, Olivier M, Lopez J, Houser S, Xiao G, Kumar GS, Tomasz M, Bargonetti J.  Differential activation of p53 by the various adducts of mitomycin C.  J Biol Chem. 2002 Oct 25;277(43):40513-9.

Zhong M, Lu Z, Abbas T, Hornia A, Chatakondu K, Barile N, Kaplan P, Foster DA. Novel tumor-promoting property of tamoxifen.  Cell Growth Differ. 2001 Apr;12(4):187-92.

Nidhi Gadura, Ph.D.  (2004)
Currently: Assistant Professor, Queensborough Community College, CUNY
Mentor at CUNY: Dr. Corinne Michels, Queens College

Publications at CUNY
Gadura, N., L.C. Robinson, and C.A. Michels, 2006. Yck1,2 casein kinase type-1 signals to Glc7-Reg1 protein phosphatase to regulate the transport activity and glucose-induced inactivation of Saccharomyces maltose permease. Genetics 170: 1427-1439.

Gadura, N. and C.A. Michels, 2006. Sequences in the N-terminal cytoplasmic domain of Saccharomyces cerevisiae maltose permease are required for vacuolar degradation but not glucose-induced internalization. Curr. Genet. 50: 101-14.

Jianjun Wang, Ph.D.  (2004)
Currently: Postdoctoral Research Associate, Thomas Jefferson University, Philadelphia, PA
Mentor at CUNY: Dr. Cathy Savage-Dunn, Queens College

Publications at CUNY
Wang, J., W.A. Mohler and C. Savage-Dunn. 2005. C-terminal mutants of C. elegans Smads reveal tissue-specific requirements for protein activation by TGF-b signaling. Development, 132:3505-3513.

Wang, J., R. Tokarz and C. Savage-Dunn. 2002. The expression of TGFb signal transducers in the hypodermis regulates body size in C. elegans. Development 129:4989-4998.

Selwyn A. Williams, Ph.D. (2004)
Currently: Assistant Professor of Biology, New York City College of Technology, CUNY
Mentor: Ray Gavin, Brooklyn College

Publications at CUNY
Williams, S.A. and Gavin, R.H. (2005) Myosin genes in Tetrahymena thermophila. Cell Motil. Cytoskel. 61: 237-243.
 
Hosein, R.E., Williams, S.A., and Gavin, R.H. 2005. Directed motility of phagosomes in Tetrahymena thermophila requires actin and Myolp, a novel unconventional myosin. Cell Motil. Cytoskel. 61:49-60
 
Garcés, J. A., Williams, S. A., and Gavin, R. H. 2003. Chromosome Walking by Inverse PCR. In: Weissensteiner, T. (ed.), PCR Technology: Current Innovations, 2nd Edition. CRC Press, London
 
Hosein, R. E., Williams, S. A., Haye, K. A., and Gavin, R. H. 2003. Expression of GFP-actin leads to failure of both nuclear elongation and cytokinesis in Tetrahymena thermophila J. Eukot. Microbiol. 50: 394-399
 
Williams, S. A., Hosein, R. E., Garces, J. A., and Gavin, R. H. 2000. MYO1, a novel unconventional myosin gene affects endocytosis and macronuclear elongation in Tetrahymena thermophila. J. Eukot. Microbiol. 47:561-568.

Marco Domeniconi, Ph.D.  (2003)
Currently: Postdoctoral Fellow, New York University Medical School, New York, NY
Mentor at CUNY: Dr. Marie Filbin, Hunter College

Publications at CUNY
Domeniconi M, Zampieri N, Spencer T, Hilaire M, Mellado W, Chao MV, Filbin MT.  MAG induces regulated intramembrane proteolysis of the p75 neurotrophin receptor to inhibit neurite outgrowth.  Neuron. 2005 Jun 16;46(6):849-55.

Domeniconi M, Filbin MT.  Overcoming inhibitors in myelin to promote axonal regeneration.  J Neurol Sci. 2005 Jun 15;233(1-2):43-7.

Spencer T, Domeniconi M, Cao Z, Filbin MT.  New roles for old proteins in adult CNS axonal regeneration.  Curr Opin Neurobiol. 2003 Feb;13(1):133-9.

Domeniconi M, Cao Z, Spencer T, Sivasankaran R, Wang K, Nikulina E, Kimura N, Cai H, Deng K, Gao Y, He Z, Filbin M.  Myelin-associated glycoprotein interacts with the Nogo66 receptor to inhibit neurite outgrowth.  Neuron. 2002 Jul 18;35(2):283-90.

Melissa C. Garcia, Ph.D. (2003)
Currently: Postdoctoral Fellow, National Institutes of Health, Bethesda, MD
Mentor at CUNY: Dr. Qi He, Brooklyn College

Publications at CUNY
Garcia, M.C., Abbasi, M., Singh, S. and He, Q. (2007) Role of Drosophila gene dunc-115 in nervous system. Invert. Neurosci. 7, 119-128.

Richard Paul Sorrentino, Ph.D.  (2003)
Currently:  Postdoctoral fellow, University of Texas M.D. Anderson Cancer Center, Houston, TX
Mentor at CUNY:  Dr. Shubha Govind, City College of New York

Publications at CUNY
Chiu H*, Sorrentino RP*, Govind S.  Suppression of the Drosophila cellular immune response by Ganaspis xanthopoda.  In Advances in Experimental Medicine and Biology:  Phylogenetic perspectives on the vertebrate immune system. 2001 v. 484, pp. 161 – 168.  Kluwer Academic Publications, New York.  (Beck G, Sugumaran M, and Cooper EL, eds.) (* co-authors)

Sorrentino RP, Carton Y, Govind S.  Cellular immune response to parasite infection in the Drosophila lymph gland is developmentally regulated.  Dev. Biol. 2002 43(1):65-80.

Sorrentino RP, Small CN, Govind S.  Quantitative analysis of phenol oxidase activity in insect hemolymph.  BioTechniques. 2002 32(4):815-823.

Sorrentino RP, Melk JP, Govind S.  2004.  Genetic analysis of contributions of dorsal group and JAK-Stat92E pathway genes to larval hemocyte concentration and the egg encapsulation response in Drosophila.  Genetics 166(3):1343-1356.

Xen Wang, Ph.D.  (2003)
Currently: Postdoctoral Research Associate, Memorial Sloan-Kettering Cancer Center, NY
Mentor at CUNY: Dr. Corinne Michels, Queens College

Publications at CUNY
Wang, X., M. Bali, I. Medintz, and C.A. Michels, 2002. Intracellular maltose is sufficient to induce MAL gene expression in Saccharomyces cerevisiae. Eukaryot. Cell 1: 696-703.

Wang, X. and C.A. Michels, 2004. Mutations in SIN4 and RGR1 cause consitutive expression of MAL structural genes in Saccharomyces Genetics 168: 747-757.

 

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