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Basic Seminar in Biochemistry I
(Enzymology and Metabolism)
BICM 72010
Ph.D. Program in Biochemistry
Fall 2002
SCHEDULE OF SEMINARS
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DATE |
TOPIC |
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SPEAKER |
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| Aug 30 |
Organizational Meeting |
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| Sept
13 |
Protein
Purification: "Deoxyhypusine
Synthase from Rat Testis: Purification and Characterization."
Wolff, E.C. et al., J. Biol. Chem.
270, 8660-8666, 1995. |
|
Fulai Ran |
| |
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| Sept
20 |
Protein
Structure: "De Novo Design, Expression and Characterization of Felix: A
Four-Helix Bundle Protein of Native-Like Sequence." Hecht, M.H., et al.,
Science 249: 884-891, 1990 |
|
Ke Xu |
| |
|
|
|
| |
Protein
Structure: "Understanding the Sequence Determinants of Conformational
Switching Using Protein Design." Dalal, S., and Regan, L., Protein
Science 9: 1651-1659, 2000. |
|
Jinming Zhang |
| |
|
|
|
| Sept
27 |
Enzyme
Function: "Evidence that the Angiotensin IV (AT4) receptor is the Enzyme
Insulin-Regulated Aminopeptidase." Albiston, A.L., et al.,
J. Biol. Chem. 276:
48623-48626, 2001 |
|
Palgunan Kalyanaraman |
| |
|
|
|
| Oct 4 |
Enzyme Function: "The Importance of the Conserved Arg191-Asp227 Salt
Bridge of Triosphosphate Isomerase for Folding, Stability, and Catalysis."
FEBS Lett. 518: 39-42, 2002 |
|
Li Hua Qian |
| |
|
|
|
| Oct
11 |
Hemoglobin Cooperativity: "Structural,
Functional, and Subunit Assembly Properties of Hemoglobin Attleboro [a138(H21)
Ser-->Pro], a Variant Possessing a Site Mutation at a Critical C-Terminal
Residue." McDonald, M.J., et al., Biochemistry 29,
173-178, 1990. |
|
Thushara Abeyweera |
| |
|
|
|
| Oct
18 |
No
Seminar: Review Session |
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|
| |
|
|
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| Oct
25 |
No
Seminar |
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| |
|
|
|
| Nov
1 |
Glucose
Transport in Transgenic Mice: "Adipose
Cell Hyperplasia and Enhanced Glucose Disposal in Transgenic Mice
Overexpressing GLUT4 Selectivity in Adipose Tissue." Shepherd, P.R.,
et al., J. Biol. Chem. 268:
22243-22246, 1993. |
|
Xiao Huang |
| |
|
|
|
| |
Regulatory Protein of Glucokinase and Hepatic Glucose Sensing: "The
Role of the Regulatory Protein of Glucokinase in the Glucose Sensory
Mechanism of the Hepatocyte". De la Iglesia et al., J. Biol.
Chem. 275: 10597-10603, 2000 |
|
Huan Yang |
| |
|
|
|
| Nov
8 |
Subtypes
of a-Adrenergic Receptors: "Multiple
Second Messenger Pathways of a-Adrenergic
Receptor Subtypes Expressed in Eukaryotic Cells". Cotecchia et al.,
J. Biol. Chem. 275: 10597-10603, 2000 |
|
Ranata Pyzik |
| |
|
|
|
| |
Glycogen/Glucose 1-Phosphate Cycle in Hepatocytes: "Demonstration
of a Glycogen/Glucose-1-phosphate Cycle in Hepatocytes from Fasted Rats."
Massillon et al., J. Biol. Chem. 270: 19351-19356,
1995. |
|
Samuel Moto |
| |
|
|
|
| Nov
22 |
Using an
Inhibitor to Study the Organization of the Enzymes of
b-Oxidation in Mitochondria: "4-Bromotiglic
acid, A Novel Inhibitor of Thiolases and a Tool for Assessing the
Cooperation Between the Membrane-Bound And Soluble b-Oxidation
Systems of Rat Liver Mitochondria." Liang and Schulz, Biochemistry
37: 15548-15554, 1998. |
|
Lina Nie |
| |
|
|
|
| Dec
6 |
SREBP-1, a Membrane-Bound Transcription Factor Released by
Sterol-Regulated Proteolysis: Wang et al., Cell 77:
53-62, 1994 |
|
Lisette Arnaud |
| |
|
|
|
| Dec
13 |
Scientific Ethics for Graduate Students |
|
Prof. Charlotte Russell |
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