BIOCHEMISTRY COURSES
The doctoral courses are divided into two levels: those
numbered 70000 are fundamental core courses and those numbered
80000 are advanced, special topics courses and seminars.
Typically students complete the core courses and two
semesters of seminar during their first year (30 credits
of graduate courses).
Unless otherwise stated, all courses are 45 hours, 3 credits.
Biochemistry
Program Course Offerings
Biochemistry Program Core Courses
(Required of all students, except fro BICM
71130).
BICM 71010 - ADVANCED BIOCHEMISTRY I (Enzymology/Metabolism)
Protein structure, enzymology, and immunology; metabolism
of carbohydrates, lipids, amino acids, and nucleotides;
regulation of these processes.
Prerequisite: A one semester course in
biochemistry
BICM 71020 - ADVANCED BIOCHEMISTRY II
(Bioenergetics/Molecular Biology)
Membranes: structure, transport and other functions; muscle
and cytoskeletal biochemistry; bioenergetics: respiration
and photosynthesis; nucleic acids and protein synthesis.
Prerequisite: A one semester course in
biochemistry
BICM 71110 - RESEARCH TECHNIQUES IN BIOCHEMISTRY
I
4 credits
During the course of one year each student will work in
3 or 4 research laboratories to solve clearly defined biochemical
problems by use of modern research techniques.
Corequisite: BICM 71010
BICM 71120 - RESEARCH TECHNIQUES IN BIOCHEMISTRY
II
4 credits
Continuation of Biochemistry 71110
Prerequisite: BICM 71110
BICM 71130 - RESEARCH IN BIOCHEMISTRY
4 credits
One biochemistry problem will be solved by use of modern
research techniques.
Prerequisites: BICM 71110 and BICM 71120
BICM 72010 - BASIC SEMINAR IN BIOCHEMISTRY I
1 credit
Each student will present at least one published paper related
to the topics covered in BICM 71010
BICM 72020 - BASIC SEMINAR IN BIOCHEMISTRY II
1 credit
Each student will present at least one published paper related
to the topics covered in BICM 71020
BICM 75000 - BIOORGANIC CHEMISTRY
Chemistry of amino acids, sulfur and phosphates; proton
transfer; catalysis by fields, hydronium and hydroxide ions;
general acid-base catalysis; nucleophilic and electrophilic
catalysis; metal ion catalysis; intramolecular catalysis;
multiple catalysis; catalysis by complexation.
BICM 77000 – PHYSICAL BIOCHEMISTRY
Principles and applications of classical and statistical
thermodynamics, spectroscopy, kinetics and x-ray crystallography
to the study of biomacromolecular and biochemical systems.
Advanced
Courses
BICM 81000 – SEMINAR IN BIOCHEMISTRY
15 hours, 1 credit
Three semesters required of all students
BICM 82000 – DOCTORAL DISSERTATION RESEARCH
Credits variable
Prerequisite: The First Level Examination
BICM 83000 – BIOCHEMISTRY OF LIPIDS AND MEMBRANES
Purification and physical characterization of lipids and
membrane proteins; bilayer properties, lipid dynamics, transport
proteins and energy; cytoskeletal membrane proteins; receptors;
membrane-bound enzymes; signal in cells; and membrane biogenesis.
BICM 84000 - ENZYMOLOGY
Purification of enzymes; kinetic and structural properties;
mechanism of action; studies of active sites; regulation
of catalytic activity.
BICM 85000 - NUCLEIC ACID METABOLISM AND FUNCTION
Current views on the molecular structure of DNA and RNA,
their biosynthesis and degradation, their functional role
in protein synthesis and in development.
BICM 86000 – METABOLIC PATHWAYS AND THEIR
CONTROL MECHANISMS
The major metabolic pathways in plants, animals and microorganisms;
multienzyme systems and some mathematical models applicable
to them; mechanisms of regulation such as enzymic induction
and feedback inhibition.
BICM 87000 - BIOINFORMATICS
The use of bioinformatic methods to study the properties
of biological macromolecules, including proteins,
carbohydrates, lipids, cofactors, and nucleic acids.
Concentration on visualization and evolutionary and homology
relationships among macromolecular sequences and structures.
BICM 88800 – CURRENT TOPICS IN BIOCHEMISTRY
15 hours, 1 credit
Recent advances in selected areas of biochemistry will be
presented.
BICM 88900 – SPECIAL TOPICS IN BIOCHEMISTRY
Lectures dealing with specialized topics or recent advances
in the field.
BICM 90000 – DISSERTATION SUPERVISION
1 credit
Required of all students
Prerequisite: Completion of all required courses.
Top
